Carbapenem
Menopenem / Meropenem

Menopenem or Meropenem

Menopenem is a beta-lactam antibiotic classified as a Carbanepem which is used to treat infections like pneumonia and meningitis.It can also help treat urinary tract infections, skin, bone and stomach infections. Menopenem is an injectable antibiotic which acts by inhibiting cell wall synthesis of the bacteria, but it is highly resistant to degradation.

Your doctor or healthcare provider will always perform some laboratory tests and physical examination before administering the drug. The length of treatment depends on the condition of the patient and the response after administering the drug.

It does not require combination with Cilastatin and can be administered on its own, as it is stable to dehydropeptidase. It is injected into a large muscle or added to an IV fluid. The dosage depends on the condition of the patient and may vary from one to thrice a day.

It is known to act against many infections quite similar to imipenem. However, it can be more effective against some Enterobacteriaceae.

While it is given intravenously or injected, dosage is adjusted for kidney function and hemofiltration.

Like with most antibiotics, the side effects of Menopenem are diarrhoea, vomiting and nausea. It can also lead to headache, rash and thrombophlebitis and hypokalaemia. It has less potential of causing seizure as compared with imipenem, another carbanepem used for treating similar conditions.

Any prior known allergy to meropenem, penicillin, cephalexin, cephalosporins, cefadroxil should be informed to the doctor. It is also important to inform your doctor if you are taking any supplements and prescription drugs such as probenecid (Benemid) valprioc acid. If you have had any kidney disease or liver disease, bring that to your health care provider’s attention before the drug is administered. Also, for pregnant and lactating women, it is very important to check with the doctor before the drug is administered.

The drug may be given to you as vials, but before administering one has to make sure that the solution is clear and free of floating material. If the solution is turbid or coloured, please do not use this solution.

It is sold as trade name Zwipen, Carbonem and Neomed, Mepem, Carnem, Meropen, Neopenem. It treats gram-positive and gram-negative bacteria also including anaerobic bacteria. In action against bacteria it is similar to Imipenem though.

For anyone who is being administered this drug should note that this drug is not supposed to be discontinued without your doctor’s advice, as any discontinuation before the completion of the dose, may be detrimental and reverse any benefits of treatment. On the contrary it can worsen your condition.

Some of the severe symptoms threatened to be reported immediately are seizures, fatigue and sleepiness and dizziness. However, there may be some other symptoms such as upset stomach, stomach pain, indigestion, constipation, headache and diarrhoea. These are the symptoms you can watch and report to your healthcare provider.

In case of an overdose of this drug, quickly call your emergency services of your locality. Sometimes, there can be an infection at the place of receiving meropenem that is where the needle enters the vein, any sign of warmth, irritation, tenderness, swelling and drainage etc. should be brought to the attention of your health care provider. This can often be accompanied by pain.If there is an overdose, you should quickly call your emergency health services.

If you are asked to make your meropenem solution yourself, please take directions from the vial or that come with the drug. These Carbepenem antibiotics are not the first line of treatment and often are required when other do not work as the over-use may induce resistance to these life saving drugs.